ICPD Invited to Present at FDA/NIAID/IDSA Workshop on the Issues in Antibacterial Resistance and Device Development

Albany, NY, July 27, 2010 – The Institute for Clinical Pharmacodynamics (ICPD) announced that its director, Dr. Paul G. Ambrose, Pharm.D., FIDSA, participated today with other academicians, scientists and industry experts in presenting at a workshop designed to provide a forum for discussion of scientific data addressing key issues in the scale of the current bacterial resistance problem including extent, trajectory, and cost; the science and mechanisms of bacterial resistance; the science of development of rapid diagnostic devices; the science of antimicrobial drug development. The
two-day workshop, which was co-sponsored by the Food and Drug Administration (FDA), National Institute of Allergy and Infectious Diseases (NIAID), and the Infectious Diseases Society of America (IDSA), took take place on July 26 and 27, 2010 in Silver Spring, MD.

Dr. Ambrose, in his presentation which focused on the application of
PK-PD in the development of antimicrobial agents for resistant pathogens, described data demonstrating the relationship between antimicrobial drug exposure and resistance emergence and the impact that the magnitude, shape, and duration of drug exposure has on outcome. Dr. Ambrose urged the audience to consider these factors when designing regimens for
drug-resistant pathogens in order to capitalize upon a drug’s PK-PD profile to maximize bacterial eradication and clinical outcome and reduce the emergence of antimicrobial resistance.

“ICPD continues to be committed to serving the public’s need in resolving the current antimicrobial resistance crisis,” stated Dr. Ambrose, who has participated in the two recent FDA- and IDSA-sponsored workshops which centered around issues in the design and conduct of clinical trials for antibacterial drugs for community-acquired pneumonia and both
hospital-acquired and ventilator-associated pneumonia. “Each of these workshops has served to provide a forum for knowledge leaders in the field to assemble, share data and concepts, and discuss strategies that should be implemented.

About ICPD

The ICPD serves as a center for translational science collaboration to the world. We help pharmaceutical and biotechnology companies develop more effective and safer drugs through advanced methods of pharmacokinetic and pharmacodynamic system analysis. Our general contact information is as follows:

Telephone: (518) 429-2600
Info@ICPD.com